This page lists the various street names found in and around Empire Bay. Only a handful of streets in Mafia II are actually named and most have little information given about them. What is known is listed below.
Empire Bay Highway
Empire Bay Highway is a large four lane highway providing a quick way around the city. It starts in Uptown, on the mid-east bank of the Culver River and ends Riverside. There are highway exits in Little Italy, North Millville and Southport. The speed limit throughout the highway is 70 mph.
Jenkins Street is in North Millville. Its exact location is unknown as it's only mentioned in the Frankie Potts files when it appears in a photograph depicting the Empire Bay Police Department arresting a greaser outside his house on Jenkins Street. Since the house in the photograph doesn't exist in the game, it's assumed that Jenkins Street is located outside of the map.
Main Street is where Frankie Potts lived; its exact location is unknown.
Palisade Street is located in Southport, Bruno's office is on this street as is the entrance to the Docks. There is also a McClusky & Son gun store located on the street. The street ends where the Southport Tunnel starts.
River Street is located in Kingston. The Scetta Apartment is on this street and is the street parallel to Kingston Stadium. Going east on the street will eventually take you to the start of the Empire Bay highway.