The Irish Mob is run by Thomas Burke and operates out of Pointe Verdun. They are also one of the three criminal organizations who help Lincoln Clay in his quest of taking down the Marcano Crime Family.
- Thomas Burke (boss)
- Danny Burke (lieutenant, deceased)
- Nicki Burke (lieutenant)
- Terry Daly (associate)
- Fiona Davidson (associate)
- Hank McGahee (associate)
- Bear Donnelly (formerly)
- Nicki Burke will become the boss if her father is killed.