Located in the hills to the north of the city, it is a wealthy neighborhood consisting mostly of mansions.
Locations of Interest
- There is a house on the cliffs overlooking Little Italy, just above the Empire Bay Highway, that is identical to the one in the 1960 film Psycho.
- There are nine wanted posters in Highbrook for the player to find.
- The gates on most of the mansions in Highbrook are locked and cannot be opened by hand; as such the only way to access the mansions' yards is to smash through the gate with a vehicle.