The Vizzini crime family were a powerful branch of the Sicilian Mafia, based in the Province of Caltanissetta led by Don Calò. They were founded some time in the 1800s in Sicily. In 1914 Don Calò became the boss of the family. Under his control the Vizzini family became the most powerful Mafia family in Sicily.
World War II
On July 11th, 1943, while Vito's squad was being pinned down by Italian blackshirts (forces loyal to Benito Mussolini), Don Calò started to speak from a tank informing the Italians that they should trust the Americans and together they could bring an end to Il Duce's rule. Don Calò is believed to be very respected because as Vito states: "Don Calò, the head of the Sicilian mafia. An entire garrison of troops surrendered that day. Why? Because he told 'em to". Even Joe who lives overseas in Empire Bay has heard of Don Calò, this shows that he is well known and connected.
- Don Calogero Vizzini is the only real-life person in the Mafia series.